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Aclasta Infusion

Bone density

Aclasta infusions in Brisbane for the treatment of Osteoporosis and Bony Diseases

Osteoporosis is a long-term disease which makes your bones less dense and more fragile. If you have osteoporosis, you are more likely to fracture or break a bone if you have a mild injury or minor fall.

Some doctors, medical specialists or patients choose Zoledronic Acid (Aclasta TM) intravenous infusion as the preferred treatment for osteoporosis. Aclasta TM is a form of bisphosphonate. The infusion usually only needs to be done once a year (but can be varied by your specialists).

Aclasta TM works by slowing down bone resorption, which allows the bone- forming cells time to rebuild normal bone. This allows bone remodeling to go back to normal and protects the bones from being weakened.

Bone density

Aclasta Treatment

To qualify for Aclasta TM Infusion for treatment of Osteoporosis, under Pharmaceutical Benefits Scheme (PBS), one need to be diagnosed with:

Osteoporosis as per criteria below:

  • 70 years or older with bone mineral density (BMD)score “T score” of less than -2.5, or
  • Established osteoporosis with any fracture due to minimal trauma, or


Corticosteroid – induced osteoporosis as per criteria below:

  • Patient on long-term high-dose (≥ 3 months at ≥ 7.5 mg daily prednisolone or equivalent) corticosteroid therapy and with a BMD T-score ≤ –1.5.


Aclasta TM may have a particular role for people in whom an oral bisphosphonate is unsuitable or not tolerated, such as those who:

  • Are unable to stay upright for at least 30 minutes after a dose
  • Have an oesophageal (gullet) disorder that precludes use of an oral bisphosphonate
  • Are experiencing intolerable gastrointestinal upset or other oesophageal (gullet) adverse effects.


Often patients prefer a once-a-year Aclasta TM infusion to regular oral tablets over a one-year period (as one may not always remember to take the tablets).

Aclasta TM is found to be similar in efficacy to ProliaTM (Denosumab), another injectable, in treating osteoporosis.  However, the increased bone density achieved by Aclasta TM infusion is often long- standing and relatively well preserved, which is different in nature to that of Prolia’s.

Prolia needs to be given almost indefinitely, every 6 months, to maintain the increased bone density. The reason for this is once Prolia injections stop, there is an increase in bone turnover and rapid bone resorption. Stopping Prolia can cause an increase in the number of fractures, often within a year of stopping.

Aclasta TM infusions is also used to treat a range of other medical conditions including symptomatic Paget’s Disease, hypercalcaemia due to cancer, bone break down due to cancer, Duchene Muscular dystrophy and multiple other conditions (as approved by your treating medical specialists).


AclastaTM infusion Appointments

The first consultation

We will review your medical condition (s), and if appropriate, arrange consent for an Aclasta TM infusion.

It will be appreciated if you can obtain from your referring doctor a copy of:

  • Latest Bone Density Scan (DEXA Scan)
  • Latest blood tests that include your renal function, calcium level and Vitamin D level.


Aclasta Infusion consultation

The second consultation is for the actual Aclasta TM infusion. Your doctor / nurse will insert a cannula, usually into your arm using a clean / aseptic technique.

The infusion process normally takes about 20 – 30 minutes and in general, you have to be observed for a further period of time after the infusion.


Patient Form:

Aclasta Infusion Advice Sheet

Book an appointment for Aclasta Infusion

Medical Specialist Referrals

We welcome referrals from medical specialists. If you are a medical specialist and you would like to refer your patient to us for an Aclasta TM Infusion, we appreciate if you can complete the Referral Form for Aclasta Zoledronic Acid Infusion.

It will be appreciated if you can provide your patient with:

  1. Aclasta TM script
  2. Report of the Bone Density (DEXA) Scan for PBS eligibility (if it is for osteoporosis)
  3. Latest renal function and electrolytes including Calcium level and Vit D level.


Patient Info

Brisbane Aclasta Infusions: Please note prior to an Aclasta infusion you require an initial consultation with one of our GP’s. Feel free to contact our team should you have any queries.

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